Package | Dosage | Price | Price per Dose | |
---|---|---|---|---|
Dosage: 10/100mg | ||||
360 pill | 10/100mg | €217.35 | €0.60 | |
180 pill | 10/100mg | €120.75 | €0.67 | |
120 pill | 10/100mg | €91.42 | €0.76 | |
90 pill | 10/100mg | €75.90 | €0.85 | |
60 pill | 10/100mg | €57.78 | €0.97 | |
30 pill | 10/100mg | €34.49 | €1.16 | |
Dosage: 25/100mg | ||||
360 pill | 25/100mg | €254.44 | €0.71 | |
180 pill | 25/100mg | €144.04 | €0.80 | |
120 pill | 25/100mg | €109.54 | €0.91 | |
90 pill | 25/100mg | €90.56 | €1.01 | |
60 pill | 25/100mg | €69.86 | €1.16 | |
30 pill | 25/100mg | €43.12 | €1.42 | |
Dosage: 25/250mg | ||||
360 pill | 25/250mg | €294.98 | €0.82 | |
180 pill | 25/250mg | €167.33 | €0.93 | |
120 pill | 25/250mg | €131.10 | €1.10 | |
90 pill | 25/250mg | €108.67 | €1.21 | |
60 pill | 25/250mg | €80.21 | €1.34 | |
30 pill | 25/250mg | €45.71 | €1.51 |

Carbidopa / Levodopa Description
Overview of Carbidopa / Levodopa
Carbidopa / Levodopa is a combination medication commonly prescribed for the management of Parkinson’s disease. This medication helps to alleviate the symptoms caused by the reduction of dopamine levels in the brain. Levodopa is a precursor to dopamine, meaning it is converted into dopamine once inside the brain, helping to restore the neurotransmitter balance. Carbidopa is added to prevent the premature conversion of Levodopa outside the brain, which allows more Levodopa to reach the target area and reduces some side effects such as nausea and vomiting.
How the Medication Works
The primary function of Levodopa in this combination is to replenish dopamine levels, which are critically low in Parkinson’s patients. Dopamine itself cannot cross the blood-brain barrier, but Levodopa can. Once in the brain, Levodopa is converted into dopamine, relieving motor symptoms such as tremors, rigidity, and bradykinesia. Carbidopa works by inhibiting an enzyme, dopa decarboxylase, which causes the breakdown of Levodopa before it reaches the brain. This allows a greater proportion of Levodopa to reach the brain, increasing efficacy and reducing peripheral side effects.
Benefits and Effectiveness
Many patients find Carbidopa / Levodopa highly effective in controlling the motor symptoms of Parkinson’s disease. It provides significant improvement in daily functioning and quality of life. The medication's benefits depend on proper dosing and adherence to the prescribed regimen. Over time, some patients may experience fluctuations in their response, with periods of 'on' times when symptoms are controlled and 'off' times when symptoms worsen. Nonetheless, it remains one of the most potent therapies available for Parkinson’s disease management.
Possible Side Effects
As with any medication, Carbidopa / Levodopa may cause side effects. Common adverse effects include nausea, dizziness, and dry mouth. Some patients report involuntary movements, such as twitching or jerking, especially at higher doses. Long-term use can sometimes lead to motor complications like dyskinesias. Less frequently, patients may experience psychiatric symptoms such as hallucinations or confusion. It is essential to monitor patients regularly to adjust doses and minimize side effects.
Precautions and Interactions
This medication should be used cautiously in patients with cardiovascular issues, psychiatric disorders, or malignant melanoma. It interacts with several other medications, including certain antipsychotics, antidepressants, and iron supplements, which can affect its efficacy or increase side effects. Patients are advised to inform their healthcare provider of all medications they are taking. Additionally, lifestyle modifications and dietary restrictions may be recommended to optimize treatment outcomes.
Conclusion
Carbidopa / Levodopa remains a cornerstone in Parkinson’s disease therapy. Its ability to improve motor function and reduce symptoms significantly enhances patients’ quality of life. However, careful management is crucial to balance benefits and minimize side effects. Regular medical supervision helps ensure the medication’s effectiveness over the long term, making it a vital option for many individuals living with Parkinson’s disease.